Zantac® linked to Cancer

The active ingredient ranitidine that had been used in Zantac® can convert to the carcinogen NDMA and lead to cancer or other health conditions. Thousands have already filed lawsuits. If you or a loved one developed a serious health condition and previously took Zantac, contact us to find out if you might have a legal case.

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What Is the zantac recall All About?

Zantac is the brand name for ranitidine, an antacid that belongs to a group of medications known as H2-receptor antagonists widely used to reduce the production of stomach acid in patients with gastroesophageal reflux disease (GERD) and peptic ulcer disease. In April 2020, the U.S. Food and Drug Administration (FDA) announced it was requesting manufacturers to immediately withdraw all prescription and over-the-counter (OTC) ranitidine products from the market after an ongoing investigation of the contaminant N-Nitrodimethylamine (NDMA) in ranitidine medications. Ranitidine is no longer available for sale in the U.S.

What is the reason for the Zantac recall?

A Zantac recall was issued, and all ranitidine products were withdrawn from the market because of the presence of NDMA, a cancer-causing impurity.


Studies show NDMA in ranitidine increases over time and under higher than room temperature storage conditions. Testing showed NDMA levels in Zantac were as much as 9 times greater than the FDA’s recommended limit.


NDMA is classified by the International Agency for Research on Cancer (IARC) as a probable human carcinogen (group 2A). A number of different cancers have been linked to the use of ranitidine (Zantac).

Which cancers have been linked to Zantac?

Zantac with ranitidine has been linked to a number of types of cancer, including:

  • Bladder cancer
  • Esophageal cancer
  • Gastric/stomach cancer
  • Liver cancer
  • Pancreatic cancer

Numerous animal studies conducted on NDMA found various species, including rats and mice, have developed tumors in the liver, respiratory tract, and blood vessels after NDMA exposure.

What is the Zantac lawsuit about?

Thousands of Zantac lawsuits have been filed coast-to-coast. Lawsuits claim a design defect in Zantac, as the active ingredient, ranitidine, is an unstable molecule. In addition, lawsuits claim that manufacturers failed to properly warn the public about cancer risks associated with the product.


Many of the lawsuits filed have been consolidated into federal multidistrict litigation (MDL). Compensation may be available for medical bills and expenses, including travel for treatment, lost wages, loss of ability to earn, pain and suffering. If a loved one has died as a result of cancer caused by Zantac, compensation may be available for funeral and burial expenses and loss of a loved one.

Are there any alternatives to Zantac?

The FDA issued a statement on November 1, 2019, that consumers taking OTC Zantac (ranitidine) can consider other OTC products approved for their condition. FDA testing showed no NDMA in alternatives:

  • Pepcid (famotidine)
  • Tagamet (cimetidine)
  • Nexium (esomeprazole)
  • Prevacid (lansoprazole)
  • Prilosec (omeprazole)

Zantac 360˚® has been reformulated with famotidine.


Patients taking prescription ranitidine should speak to their healthcare provider about other treatment options.

Who can file a Zantac Legal Claim?

If you have developed one of the known cancers linked to Zantac (including Bladder, Esophageal, Liver, Pancreatic or Stomach cancers) after regular use of Zantac, you could potentially be entitled a legal claim.


Find out quickly and easily if you qualify for a Zantac legal claim with a free case review:

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